2,212 research outputs found

    Avoidance of Completed Real Estate Foreclosures in Bankruptcy

    Get PDF
    The Eighth Circuit has ruled that in certain situations noncollusive real estate foreclosures can be set aside as fraudulent conveyances. This theory has generated considerable debate, but even if it is reversed legislatively trustees may be able to obtain comparable results under a preference theory

    Genetic and environmental influences on sleep quality in middle‐aged men: a twin study

    Full text link
    Poor sleep quality is a risk factor for a number of cognitive and physiological age-related disorders. Identifying factors underlying sleep quality are important in understanding the etiology of these age-related health disorders. We investigated the extent to which genes and the environment contribute to subjective sleep quality in middle-aged male twins using the classical twin design. We used the Pittsburgh Sleep Quality Index to measure sleep quality in 1218 middle-aged twin men from the Vietnam Era Twin Study of Aging (mean age = 55.4 years; range 51-60; 339 monozygotic twin pairs, 257 dizygotic twin pairs, 26 unpaired twins). The mean PSQI global score was 5.6 [SD = 3.6; range 0-20]. Based on univariate twin models, 34% of variability in the global PSQI score was due to additive genetic effects (heritability) and 66% was attributed to individual-specific environmental factors. Common environment did not contribute to the variability. Similarly, the heritability of poor sleep-a dichotomous measure based on the cut-off of global PSQI>5-was 31%, with no contribution of the common environment. Heritability of six of the seven PSQI component scores (subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, and daytime dysfunction) ranged from 0.15 to 0.31, whereas no genetic influences contributed to the use of sleeping medication. Additive genetic influences contribute to approximately one-third of the variability of global subjective sleep quality. Our results in middle-aged men constitute a first step towards examination of the genetic relationship between sleep and other facets of aging.Accepted manuscrip

    Incommensurate-commensurate transition in the geometric ferroelectric LaTaO4

    Get PDF
    Funding: UK Engineering and Physical Sciences Research Council (Grant Number(s): EP/P022637/1, EP/K503162/1), Science and Technology Facilities Council (Grant Number(s): RB1820307), China Scholarship Council (CN).The layered perovskite LaTaO4 has been synthesized to be stable in both (polar) orthorhombic and (nonpolar) monoclinic polymorphs at ambient conditions. Although the structural transition between monoclinic and orthorhombic phases has been well established, there is some controversy regarding a further, unidentified transition around 500 K. Here this is identified as an incommensurate–commensurate first‐order transition between incommensurate Cmc21(α00)0s0 and commensurate Cmc21 orthorhombic phases. Transmission electron microscopy indicates partially ordered stacking of different structural units in a, identifying the local cause for the modulation, whereas variable temperature powder neutron diffraction has shown the overall macroscopic modulation vector, q ≈ (0.456, 0, 0)—roughly a 2.2 × expansion in a, corresponding to an approximate 11a commensurate superunit cell dimension. The modulation shows a continuous temperature dependence until transitioning to the basic (commensurate) cell at TIC‐C. Doping the interlayer La sites with smaller Nd cations stabilizes the incommensuration to higher temperature, suggesting the modulation is geometrically driven at the A site.Publisher PDFPeer reviewe

    Relationship of Metabolizable Protein Balance, Purine Derivative Excretion, and 3-Methyl Histidine Excretion to Feed Efficiency in Individually Fed Finishing Heifers

    Get PDF
    Individually fed heifers were used to determine the relationship of 3-methyl histidine, purine derivatives, and metabolizableprotein balance to feed efficiency. Heifers were fed finishing dietsthat were either deficient or sufficient in metabolizable protein. Urine samples were collected and analyzed for early, late, and entire feeding period concentrations of 3-methyl histidine, purine derivatives, and creatinine. Results from this study indicated a negative relationship between feed efficiency and metabolizable protein balance, and no relationship between 3-methyl histidine excretion and feed efficiency, suggesting that protein turnover and microbial protein synthesis are not related to feed efficienc

    Relationship of Metabolizable Protein Balance, Purine Derivative Excretion, and 3-Methyl Histidine Excretion to Feed Efficiency in Individually Fed Finishing Heifers

    Get PDF
    Individually fed heifers were used to determine the relationship of 3-methyl histidine, purine derivatives, and metabolizableprotein balance to feed efficiency. Heifers were fed finishing dietsthat were either deficient or sufficient in metabolizable protein. Urine samples were collected and analyzed for early, late, and entire feeding period concentrations of 3-methyl histidine, purine derivatives, and creatinine. Results from this study indicated a negative relationship between feed efficiency and metabolizable protein balance, and no relationship between 3-methyl histidine excretion and feed efficiency, suggesting that protein turnover and microbial protein synthesis are not related to feed efficienc

    Massive scalar field in multiply connected flat spacetimes

    Full text link
    The vacuum expectation value of the stress-energy tensor 0Tμν0\left\langle 0\left| T_{\mu\nu} \right|0\right\rangle is calculated in several multiply connected flat spacetimes for a massive scalar field with arbitrary curvature coupling. We find that a nonzero field mass always decreases the magnitude of the energy density in chronology-respecting manifolds such as R3×S1R^3 \times S^1, R2×T2R^2 \times T^2, R1×T3R^1 \times T^3, the M\"{o}bius strip, and the Klein bottle. In Grant space, which contains nonchronal regions, whether 0Tμν0\left\langle 0\left| T_{\mu\nu} \right|0\right\rangle diverges on a chronology horizon or not depends on the field mass. For a sufficiently large mass 0Tμν0\left\langle 0\left| T_{\mu\nu} \right|0\right\rangle remains finite, and the metric backreaction caused by a massive quantized field may not be large enough to significantly change the Grant space geometry.Comment: 19 pages, REVTeX, 5 figures in separate uuencoded compressed fil

    Predictors of fetal anemia and cord blood malaria parasitemia among newborns of HIV-positive mothers

    Get PDF
    Background: Malaria and HIV infections during pregnancy can individually or jointly unleash or confound pregnancy outcomes. Two of the probable outcomes are fetal anemia and cord blood malaria parasitemia. We determined clinical and demographic factors associated with fetal anemia and cord blood malaria parasitemia in newborns of HIV-positive women from two districts in Ghana. Results: We enrolled 1,154 antenatal attendees (443 HIV-positive and 711 HIV-negative) of which 66% were prospectively followed up at delivery. Maternal malaria parasitemia, and anemia rates among HIV+ participants at enrolment were 20.3% and 78.7% respectively, and 12.8% and 51.6% among HIV- participants. Multivariate linear and logistic regression models were used to study associations. Prevalence of fetal anemia (cord hemoglobin level < 12.5 g/dL) and cord parasitemia (presence of P. falciparum in cord blood at delivery) were 57.3% and 24.4% respectively. Factors found to be associated with fetal anemia were maternal malaria parasitemia and maternal anemia. Infant cord hemoglobin status at delivery was positively and significantly associated with maternal hemoglobin and gestational age whilst female gender of infant was negatively associated with cord hemoglobin status. Maternal malaria parasitemia status at recruitment and female gender of infant were positively associated with infant cord malaria parasitemia status. Conclusions: Our data show that newborns of women infected with HIV and/or malaria are at increased risk of anemia and also cord blood malaria parasitemia. Prevention of malaria infection during pregnancy may reduce the incidence of both adverse perinatal outcomes. © 2013 Laar et al.; licensee BioMed Central Ltd

    The under-appreciated world of the serpin family of serine proteinase inhibitors

    Get PDF
    In the practice of medicine, many fundamental biological pathways that require tight on/off control, such as inflammation and circulatory homeostasis, are regulated by serine proteinases, but we rarely consider the unique protease inhibitors that, in turn, regulate these proteases. The serpins are a family of proteins with a shared tertiary structure, whose members largely act as serine protease inhibitors, found in all forms of life, ranging from viruses, bacteria, and archaea to plants and animals. These proteins represent up to 2-10% of proteins in the human blood and are the third most common protein family
    corecore